Seminar: Cardiac biomarker estimation in Anorexia Nervosa
Adolescent girls with AN undergo high levels of stress, which has been shown as risk factor in the development of eating disorders. Widely examined autonomic indices for stress reactivity are heart rate (HR) and heart rate variability (HRV, RR intervals (RRI) in electrocardiogram). The current state of the art concerning HRV as a biomarker for AN show consistently elevated beat-by-beat variance for AN compared to controls. Thus, HRV features may act as a discriminating biomarker and may be used as input feature to different AI methods.
In a pilot study, in collaboration with the Universitätsklinikum Erlangen (Abteilung Kinder- und Jugendpsychatrie), we will estimate possible biomarkers from HRV measurements over the course of a body confrontation intervention and whole therapy block (3-4 interventions) in AN patients. Information on stress reactivity in general, and in relation to potentially stressful situations alias body confrontation are analyzed and possible correlations and risk predictions can be derived.
- Learn concepts of HRV analysis
- Develop corresponding algorithms
- Apply biomarker estimations
|ECTS||2.5, 5, 7.5|
|Period||Winter term 2021/2022|
|Presence time||Virtual, working from remote, depending on the needs|
|Useful knowledge||Python programming|
|Work distribution||60% programming, 30% algorithms, 10% theory|
|Med. Eng. designation||Advanced Context Recognition (ACR)|
|First meeting||online-introduction-vorbesprechung-of-winter-term-2021/22-seminars, on 19th October 2021 at 16:00|
Literature recommendations are provided during the meetings. The candidate is further encouraged to research relevant publications on this topic.
Final presentation and final report