Seminar: Cardiac biomarker estimation in Anorexia Nervosa
Background
Adolescent girls with AN undergo high levels of stress, which has been shown as risk factor in the development of eating disorders. Widely examined autonomic indices for stress reactivity are heart rate (HR) and heart rate variability (HRV, RR intervals (RRI) in electrocardiogram). The current state of the art concerning HRV as a biomarker for AN show consistently elevated beat-by-beat variance for AN compared to controls. Thus, HRV features may act as a discriminating biomarker and may be used as input feature to different AI methods.
Aim
In a pilot study, in collaboration with the Universitätsklinikum Erlangen (Abteilung Kinder- und Jugendpsychatrie), we will estimate possible biomarkers from HRV measurements over the course of a body confrontation intervention and whole therapy block (3-4 interventions) in AN patients. Information on stress reactivity in general, and in relation to potentially stressful situations alias body confrontation are analyzed and possible correlations and risk predictions can be derived.
Learning Objectives
- Learn concepts of HRV analysis
- Develop corresponding algorithms
- Apply biomarker estimations
Data
| Project type | Seminar |
| ECTS | 2.5, 5, 7.5 |
| Language | English/ German |
| Period | Winter term 2021/2022 |
| Presence time | Virtual, working from remote, depending on the needs |
| Useful knowledge | Python programming |
| Work distribution | 60% programming, 30% algorithms, 10% theory |
| Med. Eng. designation | Advanced Context Recognition (ACR) |
| StudOn link | https://www.studon.fau.de/crs3987963_mem.html |
| First meeting | online-introduction-vorbesprechung-of-winter-term-2021/22-seminars, on 19th October 2021 at 16:00 |
| Registration | via StudOn |
Literature
Literature recommendations are provided during the meetings. The candidate is further encouraged to research relevant publications on this topic.
Examination
Final presentation and final report
Contact
Lena Uhlenberg
- Job title: Researcher
- Address: Henkestraße 91, Haus 7, 1. OG
91052 Erlangen
Germany - Phone number: +49 9131 85-23605
- Email: lena.uhlenberg@fau.de